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Coriell Institute Teams With IBM to Advance Personalized Medicine

ARMONK, N.Y. CAMDEN, N.J. July 15, 2011 IBM

http://www.prnewswire.com/news-releases/coriell-institute-teams-with-ibm-to-advance-personalized-medicine-125617208.html

As a result, Coriell can now better protect millions of genetic samples while also increasing its capacity to manage the volume of data generated by analyzing the genomes of large and diverse populations needed to examine the causes of critical diseases such as diabetes, cancer, and heart disease.

 

Coriell’s ‘Big Data’ challenge

Scott Megill

Overall storage costs reduced by more than 30 percent

Coriell needed to address the challenge of supporting data collections generated from more than two million ampules of cells, one million vials of DNA, and hundreds of thousands of other biomaterials.   In addition, the Coriell Personalized Medicine Collaborative Research Study – which captures an individual’s genetic differences to better understand causes for diseases – created an additional data challenge to the Institute.  Each participant in the study is genotyped using an array-based technology producing more than two million points of data, equaling approximately 1.5 GB of information per person.  With a target goal of 100,000 participants for the study, Coriell faced a massive information storage demand that was simply too cost prohibitive using legacy storage platforms.

In order to meet the challenges of a biobanking center that supports national and international scientific research, Coriell also looked to IBM to provide a process tracking system to quickly and easily adapt to the nuances of such a diverse biological collection. Layered with Coriell’s inventory management system, IBM software allows Coriell to electronically track each sample as it moves through various laboratory processes. These samples vary greatly in type, disease state, age, and other characteristics, and the ability to quickly pinpoint the location and specific processing stage of a particular sample provides a key advantage to Coriell.  

Critical response times for freezer failures significantly reduced

Today, with the deployment of a new sensor array and IBM’s monitoring software, Coriell has the ability to monitor real time freezer parameters, helping Coriell to proactively intercede before unit failure, effectively removing risk to the samples.  In addition, Coriell now has the capability to understand the impact of those events on each individual sample. A wireless probe array installed in the nitrogen tanks, incubators, and freezers feeds data to a central monitoring system in real time to give each laboratory a view into all activity taking place within the units storing samples.  

The intelligence now built into the functionality of the systems means Coriell can more effectively provide scientists with the highest-quality biological samples needed to answer their research questions.

Andy Monshaw

The complete Coriell solution is powered by IBM technology that includes: IBM XIV Storage System, IBM Tivoli Maximo, IBM Tivoli Netcool and IBM WebSphere Lombardi Edition.

About Coriell:

www.coriell.org Camden, NJ www.cpmc.coriell.org

http://www-03.ibm.com/innovation/us/smarterplanet/midmarket.html

Lizette Kodama

SOURCE IBM

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