Internally, Ion Torrent has already achieved read lengths in excess of 300bp and improvements in chemistry and loading are expected to increase chip utilization by five-fold. By combining additional reads with longer read lengths, the company will achieve exceptional scalability on its Ion PGM sequencing platform and expects to reach read lengths of up to 400bp in 2012.
As with the Ion 314 and Ion 316 chips, the Ion 318 chip will use simple PostLight™ sequencing chemistry, which requires no modified nucleotides, fluorescence, chemiluminescence or enzymatic cascades. As a result, Life Technologies will continue to deliver low-cost reagents and low-cost detection. The Ion 318 will also leverage four decades of exponential improvement in semiconductor technology, also known as Moore’s Law. This enables the Ion 318 to be priced the same as the Ion 316, even while delivering a 50-fold reduction in sequencing cost – less than a year after the Ion 314 launch.
Because of its simple and flexible workflow, the Ion PGM enables parallel processing of 8 samples per operator, which allows researchers to go from sample to result in less than one day, making it the fastest long read sequencers on the market. Ion 318 chips will continue to offer incredible sequencing speeds, while delivering up to 1Gb of highly accurate sequence.
The Ion Personal Genome Machine sequencer is for research use only. Not for use in diagnostic procedures.
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SOURCE Life Technologies Corporation