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Waters Unveils New Analytical Tools for Research and Routine Screening Applications at ASMS 2012

VANCOUVER, British Columbia May 21, 2012

Xevo G2-S QTof Xevo G2-S Tof

Waters also unveiled three new solutions with UNIFI: the Waters Screening Platform Solution, the Waters Pesticide Screening Application Solution and the Waters Metabolite Identification Application Solution.  These new solutions with UNIFI bring everything a laboratory needs – LC and MS hardware, software, consumables and standards and reagents – for routine, general purpose screening, for screening of pesticide residues in foods and beverages and for the separation, identification, and quantification of metabolites.  

For advancing scientific research, Waters announced new software that promises to revolutionize the way results are visualized and processed for ion mobility mass spectrometry experiments.

Brian Smith

Bringing StepWave Ion Optics Technology to Two New Xevo Mass Spectrometers

With the introduction Waters Xevo G2-S QTof and Waters Xevo G2-S Tof Mass Spectrometers, Waters is bringing the novel StepWave ion optics technology to its benchtop time-of-flight mass spectrometers.

Waters StepWave ion optics technology maximizes instrument sensitivity while minimizing routine maintenance.  It transfers ions from the ion source with the highest possible efficiency while actively filtering out undesirable neutral contaminants.  As a result MS signals are dramatically increased and, because critical components in the device stay clean for longer periods of time, quantitative results are more reproducible and laboratories experience less downtime due to routine cleaning and maintenance.

Waters Xevo TQ-S Waters SYNAPT G2-S HDMS

Chet Bowen

Since their introduction in 2008 Waters Xevo mass spectrometers have distinguished themselves on the basis of their trademark simplicity and universal ion source architecture giving scientists a wide selection of interchangeable ion sources best suited for the analysis at hand. All Xevo mass spectrometers also feature IntelliStart™ Technology, which automates MS resolution and calibration checks and monitors system performance during a run.

So whether the focus of research is on systems biology, biopharmaceutical characterization, metabolite profiling, forensic toxicology, food analysis or environmental research, Xevo mass spectrometers allow scientists to make the right decisions quickly and confidently.

Waters intends to commence shipments of both mass spectrometers in June.

New Waters Screening Platform Solution With UNIFI™

The Waters Screening Platform Solution with UNIFI is the first and only comprehensive screening solution to target, identify, quantitate and review based on a streamlined analytical workflow that enables more accurate results across a variety of applications.


New Waters Pesticide Screening Application Solution with UNIFI

The Waters Pesticide Screening Application Solution with UNIFI delivers the ease-of-use, sensitivity, stability, reproducibility, and throughput scientists need to successfully and profitably perform pesticide residue screening in a manner compliant with regulatory requirements today and in the future.

Waters Metabolite Identification Application Solution with UNIFI

Waters Metabolite Identification Application Solution with UNIFI is the world’s most comprehensive metabolite identification system assisting the biotransformation scientist in unprecedented ways in identifying and characterizing metabolites in both discovery and development environments.

Waters intends to ship the first units of the Screening Platform Solution, Pesticide Screening Application Solution, and Metabolite I.D. Application Solution with UNIFI in the fourth quarter of 2012.

New Software Maximizes the Ion Mobility Advantage

Since its introduction in 2006, many industries have employed the SYNAPT® HDMS mass spectrometer and its ion mobility capabilities to characterize highly complex samples consisting of hundreds – or even thousands – of sample components. The spectrally-rich datasets can then be mined for nuggets of information that can identify key compositional differences between samples that make decision-making much more effective and straightforward.

Waters announces the release of two software packages to extend the capability of Waters SYNAPT G2-S mass spectrometer’s capabilities. Waters HDMS Compare Software is an effective tool for making rapid binary comparisons of samples (from raw polymer products to biopharmaceuticals). Based on the separation capabilities of IMS-Tof/MS it is possible to use HDMS Compare to detect and visualize the differences between apparently identical samples. 

At the most basic level this visualization software alone may be sufficient to accept or reject a sample when compared to a standard, or to confirm the equivalence or difference between two samples of interest.

At a more complex level, the drift time and spectral information associated with the components responsible for the differentiation can be extracted from the dataset and analyzed to better understand the underlying reasons for the observed differences.

The need for this type of molecular fingerprinting is critical and applications abound including those for oil and petroleum, lubricants, polymers, biofuels, fragrances, cosmetics, and consumer electronics among many others.

The second software product for the Waters SYNAPT G2-S Mass Spectrometer is Waters High Definition Imaging (HDI) software, a new, fully integrated software suite for MALDI imaging experiments. Now for the first time, scientists can fully exploit the orthogonal dimension of separation afforded by ion mobility in an imaging experiment. HDI enables users to distinguish analytes – drugs and their metabolites, for example – from isobaric endogenous interferences.

Waters Introduces Omics Research Platform With TransOmics Informatics Software

To take on the challenges posed by systems biology research, Waters is announcing a new omics research platform aimed at harmonizing into a single platform what were once regarded as unique and separate research workflows – proteomics and metabolomics. Gone are the days where researchers working independently of one another generating parallel streams of proteomics and metabolomics data have to draw conclusions based on an incomplete molecular profile.  

Newcastle Upon Tyne, UK

Bernhard Kuster Munich, Germany

"The Progenesis LC-MS software from Nonlinear Dynamics has greatly facilitated our systematic research on drug-protein interactions since it virtually eliminates the common issue of ‘missing values’ in large-scale experiments. The very high information density created by data independent acquisition schemes in combination with ion mobility measurements on Waters SYNAPT systems further highlights the need for powerful informatics tools," he said.  "While the last 10 years of MS-based proteomics were driven by improvements in MS-hardware performance, it is my feeling that the next 10 years will be driven by informatics. I am therefore pleased to see two strong partners in the field teaming up to address this challenge."

Waters anticipates shipping the first units of its UPLC-MS systems with TransOmics Informatics Software in the fourth quarter of 2012.

Infectious Disease Researcher Receives ASMS Research Award Sponsored by Waters Corporation

Tuesday, May 22 Ileana M. Cristea Princeton $35,000 2012 marks

A Record Number of Scientific Presentations

For over 50 years, Waters Corporation (NYSE:WAT) has created business advantages for laboratory-dependent organizations by delivering practical and sustainable innovation to enable significant advancements in such areas as healthcare delivery, environmental management, food safety, and water quality worldwide.

Pioneering a connected portfolio of separations science, laboratory information management, mass spectrometry and thermal analysis, Waters technology breakthroughs and laboratory solutions provide an enduring platform for customer success.

$1.85 billion

Waters, Xevo, ACQUITY, nanoACQUITY, UNIFI, UPLC, IntelliStart, TransOmics and SYNAPT are trademarks of Waters Corporation.

SOURCE Waters Corporation

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